Interleukin-27 rs153109 polymorphism and the risk of non-small-cell lung cancer in a Chinese population
نویسندگان
چکیده
منابع مشابه
Interleukin-27 rs153109 polymorphism and the risk of non-small-cell lung cancer in a Chinese population
Non-small-cell lung cancer (NSCLC) has a multifactorial pathogenesis, and the genetic background may be one of the critical etiologic factors. Interleukin (IL)-27, a novel member of the IL-12 family, plays a vital role in antitumor immunity. The aim of the current study was to determine the association of a single nucleotide polymorphism of the IL-27 gene with the risk of NSCLC. The genotype of...
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IL-27, a new member of the IL-12 family, has been found to have antitumor effects in colorectal cancer (CRC); therefore, polymorphisms of this protein may modulate CRC carcinogenesis. So, we studied the association of single nucleotide polymorphisms of the IL-27 gene with the risk of CRC occurrence using a case-control using 600 CRC patients and matched healthy controls. The IL-27 rs153109 poly...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2016
ISSN: 1178-6930
DOI: 10.2147/ott.s93226